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Question: A patient with a serum deficiency has a mutation in the enzyme serum cholinesterase that hydrolyz…

by | Dec 5, 2023 | Posted Questions

A patient with a serum deficiency has a mutation in the enzyme
serum cholinesterase that hydrolyzes the substrate succinycholine.
This mutation results in a Km of 40 mM for the substrate for the
mutant enzyme, as compared to a 2.5 mM for the value of Km in the
normally functioning protein. What effect will this mutation have
on the reaction involving this substrate in the patient?

a. the substrate will be acted on with less efficiency in the
mutant protein relative to the normal protein

b. the substrate will be acted on with greater efficiency in the
mutant protein relative to the normal protein

c. the substrate will be acted on with the same efficiency in
the mutant enzyme relative to the normal enzyme

d. Not enough information to determine

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