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Aria Pane Part D. Chemical synapses The chemical synapse represented on the right shows two modes by which the signal of a neurotransmitter produced at the presynaptic membrane (top) is terminated. a) Explain in a few words the way the neurotransmitter is being processed at the synaptic cleft. Presynaptic vesicle with Mode O: Mode OOo b) Briefly explain why drugs that force the neurotransmitter from remaining active in the synaptic cleft have dramatic effects on the activity of the postsynaptic membrane (bottorm).