Cationic exchange resins have (negative, positive)
charges on surface and can bind to (positively, negatively) charged
drugs?
Cyclodextrins can form molecular complexes with poorly
water-soluble drugs and increase their solubility in water?
a) True
b) False
Phenytoin is a drug of high protein binding, about 90% protein
binding, in plasma. Valproic acid is known to displace a portion of
phenytoin bound to plasma proteins. Based on this information,
concurrent administration of phenytoin and valproic acid would not
affect the pharmacological effect of phenytoin because total
phenytoin concentration in plasma won’t change in the presence of
valproic acid.
a) True
b) False





