DNA polymerase has multiple mechanisms for editing and error
correction, whereas the capacity for error correction in RNA
polymerases seems to be quite limited. However, like a DNA
mutation, an RNA polymerase error in transcription can cause
production of a mutated protein. The limited error correction of
RNA polymerase seems to be inconsistent with the potentially
serious consequence of producing a protein with an altered amino
acid sequence. Select reasons that explain why error correction is
not as necessary in RNA polymerases as it is in DNA
polymerases.
Defective proteins are often degraded quickly, making their effects temporary. Single amino acid substitutions caused by errors in mRNA transcription would not affect protein function. Unlike DNA mutations, mRNA transcripts have short half-lives and are not inherited across many generations. Degradation of defective proteins activates mRNA repair pathways RNA polymerases synthesize many transcripts per gene, so only a small fraction of RNA transcripts would have errors. ch mRNA molecule is only translated once and then degraded. Incorrect At least one of the reasons you have selected does not explain why RNA polymerases do not require rigorous error correction. Transcription can produce many mRNA transcripts that then can be translated into many proteins. If only one of these mRNAs contains an error, not all the copies of that particular protein will contain an error. Additionally, mRNAs and proteins have a finite lifetime and can be degraded while DNA persists from generation to generation. Identify answers that are consistent with these features of transcription and translation.
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