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We are trying to determine the possible modes of inheritance for
some particular human disorder. We have a very small pedigree for
this disorder. Assuming the pedigree is accurate, indicate which of
the six modes of inheritance are consistent with this pedigree:

Select one or more:

X-Linked Recessive

X-Linked Dominant

Autosomal Recessive

Cytoplasmic

Autosomal Dominant

Y Linked

Refer to the pedigree below for this question. Individuals who
are shaded have the autosomal recessive disorder. Since it is a
rare disorder, assume that anyone entering the pedigree (someone
whose parents are not in the pedigree) is homozygous, unless there
is evidence to the contrary. Those who are not shaded show the
dominant phenotype. Let A and a represent the dominant and
recessive alleles, respectively. Fill in the table below to
indicate the genotype or probability function for the genotype of
each individual. Give all probabilities as fractions that are
simplified to the lowest value. Type your fractions in #/# format
without spaces. For example, one-half should be entered as 1/2.
Failure to correctly follow these directions will result in your
answer being marked as incorrect.

Fill in the table below to indicate the genotype or the genotype
probability of the individual. Two are completed as examples.

Give all probabilities as fractions that are simplified to the
lowest value. Type your fractions in #/# format without spaces.

Suppose that III-1 and III-2 have a child. What is the
probability that their first child is genotype Aa? Answer

What type of epistasis between locus A and B could be explained
by the following biochemical pathway?

	A_		B_
Yellow		Orange		Red

Select one:

single dominant epistasis

dominant/recessive epistasis

duplicate genes with cumulative effect

single recessive epistasis

duplicate recessive epistasis

duplicate dominant epistasis

We are interested in determining whether leaf traits for the
Totavi ash follow a common epistatic relationship. The observed
phenotypes are opposite leaves and alternate leaves. Which mode of
inheritance would most likely explain the data below?

Select one:

duplicate genes with cumulative effect

dominant/recessive epistasis

duplicate recessive epistasis

duplicate dominant epistasis

single recessive epistasis

single dominant epistasis

Two autosomal genes control horn color in dragons. Pure-breeding
gold-horned dragons were mated to pure-breeding silver-horned
dragons. All of the F1 were gold. The F1 were intermated and the F2
generation consisted of 138 gold, 16 silver and 96 bronze.

Choose the genetically based phenotypic ratio that should be
hypothesized to explain the F2 data.

Select one:

9:3:3:1

9:3:4

12:3:1

9:7

15:1

9:6:1

13:3

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Conduct a chi-square test to test the appropriate type of
epistasis.
In the chi-square test, what is the expected number of gold-horned
dragons? Round to two decimal places.

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Conduct a chi-square test to test the appropriate type of
epistasis.
In the chi-square test, what is the expected number of
silver-horned dragons? Round to two decimal places.

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Conduct a chi-square test to test the appropriate type of
epistasis.
In the chi-square test, what is the expected number of
bronze-horned dragons? Round to two decimal places.

Answer:

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Conduct a chi-square test to test the appropriate type of
epistasis.
In the chi-square test, what is the chi-square value? Round to
three decimal places.

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What is the number for the degrees of freedom?

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What is the critical value? Round to two decimal places.

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What is your conclusion from the chi-square test?

Select one:

Fail to reject Ho

Reject Ho