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Question: PrPc is protease sensitive. PrPSc is a misfolded form of PrPc. Why does PrPSc become protease res…

by | Dec 4, 2023 | Posted Questions

PrPc is protease sensitive. PrPSc is a misfolded form
of PrPc. Why does PrPSc become protease
resistant?

Acquired prion diseases are caused by ingestion of or exposure
to external PrPSc. How does ingested PrPSc
spread in the body? How can the variant CJD establish itself in the
brain, taking into account the blood brain barrier?

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