Question 7
In the second mutation you simulated a point mutation by
changing the 4th nucleotide from T to G. What type of mutation was
this?
|
neutral point mutation |
||
|
missense point mutation |
||
|
nonsense point mutation |
||
|
None of the above. |
2 points
Question 8
This is the third mutated version of the original DNA
“gene”:
3’ – TACTTAGTTGTTCATT – 5’
What word did you spell?
2 points
Question 9
In the third mutation you added an additional T after the 4th
nucleotide in your DNA strand. What type of mutation occurred in
your translation?
|
substitution mutation |
||
|
insertion frame shift mutation |
||
|
nonsense substitution mutation |
||
|
deletion frameshift mutation |
2 points
Question 10
This is the fourth mutated version of the original DNA
“gene”:
3’ – TACTAGTTGATCATT – 5’
What word did you spell?
2 points
Question 11
In the fourth mutation you simulated a point mutation by
changing the 10th nucleotide from T to A. What type of mutation was
this?
|
neutral point mutation |
||
|
missense point mutation |
||
|
nonsense point mutation |
||
|
None of the above. |
2 points
Question 12
Which kids of mutations do you suspect to have the greatest
consequence? Why?
Genetic Codes: Second Nucleotide in Codon 1-Letter Abbreviations Ala (alanine) Arg (arginine) Asn (asparagine) Asp (aspartate) Cys (cysteine) Gln (glutamine) Glu (glutamate) Gly (glycine) His (histidine) Ile (isoleucine) Leu (leucine) Lys (lysine) Met (methionine) Phe (phenylalanine) Pro (proline) Ser (serine) Thr (threonine) Trp (tryptophan) Tyr (tyrosine) Val (valine) Unavailable letters: B, J, O, U, X, Z UGU UAU UAC UAA Stop UGA Stop A UAG Stop UGG Trp G CAU CAC CAA CAG AAU AAC Phe UGC UUC UUA UUG CUU UCC Ser Leu UCG CGU CGC CGA CGG AGU AGC AGA AGG GGU GGC CCU His Leu CUA CCA CCG ACU GIn O CUG AUU Asn Ser AUC lle ACO AUA AUG- GUU GUC GUA GUG ACA ACG」 GCU GCC GCA GCG AAG GAU GAc ASP GAA GAG start Val Ala Glu GGA Gly © 2012 Pearson Education, Inc.
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