Select the true statements regarding antibody (specifically,
immunoglobulin G) structure. Both the Fab and Fc fragments contain
constant domains. Both the Fab and Fc fragments have variable
domains. The antigen-binding site is formed as a combination of
variable domains from one heavy and one light chain. The
antigen-binding site is located in the Fc fragment. The heavy and
light chains are linked by noncovalent and disulfide bonds.