This enzyme unwinds the double stranded DNA during replication The DNA forms – this area – after the two strands of the double helix have separated, or unzipped, during the process of DNA replication These small proteins bind to the strand and temporarily form hydrogen bonds with the base pairs This strand is continuous and is replicated toward the replication fork The small fragments of DNA are made discontinuously away from the replication fork Each NEW strand has to be replicated in this direction This enzyme replicates the new strand A small piece of RNA is added by this enzyme to the beginning of each new strand This enzyme relieves the coil during the unwinding of the DNA strand, unwinds the strand in the opposite direction. The 3′ of the DNA can not be replicated – this is known as ‘this’ conundrum? Region of repetitive nucleotide sequences at each end of a chromatid, added to protect the gaps at the 3′ end that can’t be synthesized by polymerase. Cancer cells have this over active enzyme – immortal Bacteria cells have DNA of this shape Eukaryote cells have DNA of this shape Eukaryotes cells have multiple ____, a start site of the genome being copied Nonstructural genes are able to splice themselves using this component that behaves like and enzyme and has catalytic properties.