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17. In onc mammalian ccll it is cstimated that 10,000 to 20,000 different types of mRNA can be found. Abundant mRNAs exist in many copies per ccll (up to 12,000 copies/ccll); but scarcc mRNAs (5 to 15 copies cell) can also be detected. At any instant, a snapshot of mRNA content would reveal a total of 360,000 mRNAs. The cell usually has about 10 times as many ribosomes as mRNAs. Assume 75% of the ribosomes are involved in protein synthesis at any instant in time a. What is the maximum number of proteins that could be in the process of synthesis at any instant? b. How many scarce proteins (use 5 copies/cell) could be in the process of being made? (hint: usc that 7.5 ribosomes are reading cach of the 5 mRNAs, but explain or show calculations for why you should use this). c. How many abundant proteins could be in the process of being made? (hint: use that 7.5 ribosomes are reading each of the 12,000 mRNAs, but explain or show calculations for why you should use this). d. What is the ratio of developing abundant proteins to developing scarce proteins?
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