To complete the scenario section of the final, choose a
scenario and paste it where indicated below. You may delete the
other scenarios from the body of the exam. Answer the questions
regarding the study you designed, giving the answers following each
of the questions. If one of the questions isn’t applicable to your
study, respond N/A after the question. Any additional information
about the study you’ve designed can be added at the end of the
required questions and will likely generate some extra
points.

Design an epidemiological study for only ONE of the 6 scenarios
below and provide at minimum the following information about your
study:

Scenario 1: A new vaccine (NoBola) has been
developed to prevent Ebola. Design a study that will indicate
whether or not NoBola is associated with a reduction in Ebola cases
in parts of the world where Ebola is endemic.

Please answer the above question

1• Describe exclusion criteria (e.g. in a prospective cohort
study, a person who tests positive for illness at or near baseline
must be excluded)

2• Describe how you will collect data for your study (survey,
medical records, laboratory tests, etc.)

3• Divide subjects as appropriate for your study design (i.e.
exposed/unexposed, case/control)

4• Describe outcome measure for study, how it’s calculated, and
how it’s to be interpreted (you don’t need to actually do
calculations, but provide the equations and give an example of how
they’re interpreted): For example: RR=a/(a+b) interpreted as the
risk of lung cancer in smokers is X times greater (or less) than it
is in non-smokers

5• Give justification for your study design (tell why you chose
that particular study design, why it is appropriate, and what you
hoped to learn from doing the study)

6• Brief discussion of study strengths and weaknesses including
a discussion of causal hypotheses and biases as they relate to your
study design